bms 5 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4598	BMS-5	BMS5,LIMKi 3	LIM Kinase
	BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.		LIM Kinase
T22277	BMS-P5		PAD
	BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.		PAD
T22277L	BMS-P5 free base		PAD
	BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-...		PAD
T7787	BMS817378		c-Met/HGFR
	BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).		c-Met/HGFR
T6420	BMS-707035		HIV Protease
	BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.		HIV Protease
T4696	BMS202 hydrochloride (1675203-84-5(free base))	PD-1/PD-L1 inhibitor 2 hydrochloride	PD-1/PD-L1
	BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L...		PD-1/PD-L1
T10958	Dapagliflozin-d5	BMS-512148 D5	Others
	Dapagliflozin D5 (BMS-512148 D5) is deuterated Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor.		Others
T4600	BMS-3		LIM Kinase
	BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.		LIM Kinase
T22612	BMY-14802 hydrochloride	BMS 181100 hydrochloride,BMY-14802-1,BMY 14802 hydrochloride	Sigma receptor , 5-HT Receptor , Adrenergic Receptor
	BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is an agonist of the α1-adrenergic receptor and 5-HT1A.		Sigma receptor , 5-HT Receptor , Adrenergic Receptor
T14685	BMS-986158		Epigenetic Reader Domain
	BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple negative breast cancer (TNBC) cells.		Epigenetic Reader Domain
T30525	BMS-442608	UNII-93881477KV
	BMS-442608 is a 5-HT1A part agonist.
T26847	BMS-281384
	BMS-281384 is a highly potent, phosphodiesterase 5 (PDE 5)-selective inhibitor.
T26862	BMS-902483
	BMS-902483 is a potent α7 partial agonist. BMS-902483 improved cognition in preclinical rodent models. BMS-902483 showed FLIR α7 EC50=9.3nM; α7 Electrophysiology, rat; Area EC50 = 140 nM; Peak, Area (Ymax %) = 40, 54. 5-...
T30524	BMS-442606	UNII-97L718J5KP,97L718J5KP,ZINC22060380
	BMS-442606 is a 5-HT1A part agonist.
T30489	BMS 181101	BMS181101,BMS-181101
	BMS-181101 is a novel antidepressant that has pharmacological characteristics as a serotonin reuptake inhibitor and a serotonin 5-HT receptor agonist.
T71085	BMS-824
	BMS-824 is a potent NS5A inhibitor. The 50% inhibition of HCV replicon replication for BMS-824 was approximately 5 nM, with a therapeutic index of >10,000. BMS-824 showed good specificity for HCV, as it was not active...
T14677	BMS-690514		EGFR , VEGFR , HER
	BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.		EGFR , VEGFR , HER
T63246	BMS-566419
	BMS-566419 is an acridinone-based inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH), a key enzyme for the de novo synthesis of guanosine nucleotides. BMS-566419 has clinical utility in the study of graft reject...
T68235	Beclabuvir HCl
	Beclabuvir, also known as BMS-791325, is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase. BMS-791325 inhibits recombinant NS5B proteins from HCV genotyp...
T39129	BMS-986143
	BMS-986143, an orally active, reversible BTK inhibitor with an IC50 value of 0.26 nM, is designed for autoimmune disease research. Additionally, it targets TEC, BLK, BMX, TXK, FGR, YES1, and ITK, exhibiting IC50s of 3 nM...